Word list 

DNEL: Derived no-effect level (reported separately as: worker-DNEL and general population-DNEL, for example as "worker-DNEL long-term for dermal route") 

DMEL: Derived minimal effect level

NOAEL: No observed adverse effect level

LOAEL: Lowest observed adverse effect level

Leading health effect: The toxicological effect that results in the most critical effect

Critical effect = leading health effect

STEL: Short term exposure limit (typically 15 minutes)

8 h TWA: Time weighed average

Important EU Directives

Carcinogens and mutagens directive (2004/37/EC). This directive requires that workplace exposures are avoided/minmised as fas as technically feasible.

Notes on DNEL and DMEL

For threshold substances a DNEL is a level of exposure which should not be exceeded, indicating control. 

For non-threshold substances a DMEL is a risk-related reference value that should be used for better target risk management measures.